Highly enantioselective conjugate addition of thiols using mild scandium triflate catalysis.
نویسندگان
چکیده
A Sc complex of (4S,5S)-diphenyl PYBOX 1 was found to serve as a catalyst for the asymmetric conjugate addition reactions between various thiols and 3-crotonoyl-2-oxazolidinone, affording the corresponding adducts in good yields and high enantioselectivies (up to 92% ee). A new improved method for making (4S,5S)-diphenyl PYBOX is presented.
منابع مشابه
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ورودعنوان ژورنال:
- The Journal of organic chemistry
دوره 72 14 شماره
صفحات -
تاریخ انتشار 2007